Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130) [Investigation Report]

On September 8, 2013, Posted by , In BIO, tagged in ,,,,,,,, , With Comments Off on Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130) [Investigation Report]

Lucia Cordero-Espinoza and Thilo Hagen* Section of Biochemistry, Yong Loo Lin College of Medication, Countrywide University of Singapore, Singapore 117597, Singapore ↵*Creator for correspondence (thilo_hagenatnuhs.edu.sg) Cullin-RING ubiquitin ligases (CRLs) mediate the ubiquitination of many protein substrates and focus on them for proteasomal degradation. The function of CRLs is underneath tight…