Intra-ER sorting of the peroxisomal membrane protein Pex3 depends on its luminal area [Study Report]

On September 5, 2013, Posted by , In BIO, tagged in ,,,,,,,,,, , With Comments Off on Intra-ER sorting of the peroxisomal membrane protein Pex3 depends on its luminal area [Study Report]

Pex3 is an evolutionarily conserved variety III peroxisomal membrane protein essential for peroxisome development. It is inserted into the ER membrane and sorted through an ER subdomain (the peroxisomal ER, or Per) to peroxisomes. By setting up chimeras amongst Pex3 and the kind III ER membrane protein Sec66, we have…